The crucial issue now is to eradicate immediately this tragic “statistical” anomaly and to learn lessons to inform, redesign and enhance subsequent diagnostic tools in order to achieve more positive outcomes in the future. A brighter future should be written today; however, these past practices will, undoubtedly, remain present for the foreseeable future.

If possible, could you please keep me updated on your progress, and let me know of any clinical trials involving glial cells, as I would be most eager to participate! (I review clinical trials daily via Alzheimer’s Association’s Trial Match program, but I have not yet seen one involving glial cells.)

While we’re on the subject of depression and anxiety drugs, and psychedelics, I’d like to mention another possible solution.

Many people have successfully treated their anxiety issues using ‘light and sound meditation’. This is a form of ‘perceptual deprivation’ the replacing of normal sensory stimuli with a uniform, constant stimulus. A brain undergoing perceptual deprivation can’t properly interpret the abnormal input, and will often “fill in the blanks” by creating vivid imagery and even hallucinations — something known as the Ganzfeld effect.

A person can achieve the Ganzfeld effect at home using Ganzframes — a special glasses or goggles that display pulses of colored lights that are synchronized with audio pulses played through earbuds. It’s all a pretty fascinating topic — read more about it in this article at Brighter Health: https://brighter-health.com/psychedelic-trips-without-drugs-to-treat-anxiety-and-depression/

I use psilocybin regularly and grow several of the species. I’m a nurse and have adhd and complex ptsd.
There are over 200 species of psilocybin mushrooms. And new species being discovered. Most people think of cubensis species and varieties or the psilocybe sclerotia species commonly referred to as magic truffles and legal in the Netherlands. Cubensis is one of the milder species as is the truffles. It lacks baeocystin and other chemicals found in other species. 4 species helps migraines and inflammation pain. Panaeolus cyanescens and natalenis both are about best for that.
Gymnopilus active species has a chemical that acts like mdma. But the psilocybin is lower and no baeocystin.

I will sleep on mushrooms. Some of the Asian species are very hard for me to stay alert the first 2 hours. But with a mutant, domesticated variety of cubensis called pe6 it’s like amphetamines with a show.
Our individual biochemistry and supplement, diet, everything effects it’s effects

Additionally, the influence of a deep region (i.e. thalamus) has been sometimes modeled as an hidden one, see Boly M, Moran R, Murphy M, Boveroux P, Bruno MA, Noirhomme Q, Ledoux D, Bonhomme V, Brichant JF, Tononi G, Laureys S, Friston K. Connectivity changes underlying spectral EEG changes during propofol-induced loss of consciousness. J Neurosci. 2012 May 16;32(20):7082-90. doi: 10.1523/JNEUROSCI.3769-11.2012. PMID: 22593076; PMCID: PMC3366913.

Indeed, it is likely to be a feedback loop. Smart people will venture further and in doing so will be exposed to more novel stimulus which increases their knowledge and ‘smartness’.

Rien´s argument is correct. Most of the people I know that go for long distance travels are usually sharp persons (good example the jobs mobility). It seems a bit floppy to state that the travels are a cause of a bright mind, instead of the inverse: smart people are likely to have reasons to explore different places… You are right when stating that in humans is difficult to control the crossovers of variables; however, we have to be careful when setting our scientific hypothesis.